The authors are grateful to all the clinicians who helped to organize the study at each study site. Privacy In addition, a systematic sample of every third patient with 4–6 positive items in question 1 of the MDQ was drawn from each setting. When all three parts were used, the MDQ could not be used as a screening tool in clinical settings. Despite the small sample size, the difference approached statistical significance (Fisher's exact test, p = 0.07). Thus the last question in the MDQ, necessitating moderate to severe problems due to episodes, appears to have a higher threshold for impairment. Depressive Disorders. Against a SCID diagnosis of bipolar I or II by trained research interviewers used as the “gold standard,” the sensitivity was 28.1% and the specificity was 97.2%. Hirschfeld RMA, Lewis LL, Vornik LA: Perceptions and impact of bipolar disorder: How far have we really come? Cassano GB, Akiskal HS, Savino M, Musetti L, Perugi G: Proposed subtypes of bipolar II and related disorders: with hypomanic episodes (or cyclothymia) and with hyperthymic temperament. In this study, we found that if only part one of MDQ was used, MDQ could differentiate between BD and UD, between BD-II and UD, and between BD-I and BD-II. Am J Psychiatry. Feasible screening instruments are needed to improve recognition and diagnosis of the various forms of the illness. Nevertheless, even using the standard cut-offs several patients with previously unrecognised bipolar II disorders were identified, and in fact, ignoring the last question completely resulted in lower specificity. Is the Subject Area "Bipolar disorder" applicable to this article? Affiliation Twenty‐one studies were included. PubMed Depression. Both in- and outpatients experiencing a major depressive episode were enrolled if they were between 16 and 65 years of age, had a DSM-IV or ICD-10 diagnosis of MDD based on a review of their medical records, understood the aims of the study and provided informed consent. The patients' basic socio-demographic data were collected with a questionnaire designed for the study in a clinical interview, supplemented by a review of their medical records (Table 1). In a large community cohort in Europe, the prevalence of bipolar disorder (BD-I and BD-II) based on the DSM-IV criteria was 5.5% . KS supervised the fieldwork, interviewed patients, and participated in writing the paper. Yes Discover a faster, simpler path to publishing in a high-quality journal. It was not clear if all three parts of the MDQ could be used in clinical settings in China. Erkki Isometsä. Of the 1,487 patients, 309 (20.8%) satisfied the DSM-IV criteria for BD: 118 (7.9%) for BD-I and 191 (12.8%) for BD-II. Several methodological limitations should be noted, some suggesting caution in interpreting the findings. Data were analyzed using the SPSS package, Version 17.0. Feeling extremely energized or elated. Benazzi F: Antidepressant-associated hypomania in outpatient depression: A 203-case study in private practice. No, PLOS is a nonprofit 501(c)(3) corporation, #C2354500, based in San Francisco, California, US, https://doi.org/10.1371/journal.pone.0091895. Section edited by Florian Seemüller. The internal consistency of the translated instrument was almost as good (Cronbach's alpha 0.79 vs. 0.90) as in the original validation study . Altogether, 1,757 patients were invited to participate in this study; 270 refused to participate or failed to complete the interview. No, Is the Subject Area "Emotions" applicable to this article? Change of diagnosis of monopolar, unipolar and bipolar illness. The sensitivity was considerably less than that found in the psychiatric outpatient group. Part of The questionnaire is self-administered and comprised of 5 questions. The best screening cutoff between BD-II and UD was 6, while the cutoff was 5 in an earlier study . This study assessed the sensitivity and specificity of the Mood Disorder Questionnaire as a screening instrument for bipolar spectrum disorders in a general population sample. This section is dedicated to covering all aspects of a wide range of mood disorders. This study is the first to examine an existing stress-model from the general population, in patients diagnosed with adjustment disorders, using a longitudinal design. J Affect Disord. The feature of relatively low sensitivity (0.66) and higher specificity (0.88) in this study was similar to that of other studies as well , , –. The results of the Korean study were similar to ours. The Diagnostic Assessment Service for People with Bipolar Disorders in China (DASP) is an ongoing national study initiated by the Chinese Society of Psychiatry (CSP) with the aim of developing and testing the usefulness of screening tools for BD in patients treated for MDD. Peer mentor programs (PMPs) have been associated with reduced psychiatric hospitalisation and shorter lengths of stay for those with other severe mental illnesses. 2011). The MDQ could differentiate BD-II patients from UD patients when only part one was used in the ROC curve analysis (P<0.05, AUC 0.83, Figure 2). All patients who participated in this study completed written consent forms. There were two limitations in the study. 10.1016/S0165-0327(02)00333-6. The criterion validity of the MDQ was estimated using the SEN, SPE, positive predictive value (PPV), negative predictive value (NPV) and the area under the curve (AUC). Hirschfeld RM, Williams JB, Spitzer RL, et al. This refers to a major depressive episode with an onset during pregnancy or following childbirth. Article BD is a common disorder. The Mood Disorder Questionnaire seems to be a feasible method for improving the recognition of bipolar disorder. Manage cookies/Do not sell my data we use in the preference centre. OBJECTIVE: This study tested the validity in the adult general population of the Mood Disorder Questionnaire, a screening instrument for bipolar I and II disorders.The Mood Disorder Questionnaire has been validated in a psychiatric outpatient study group. To find articles in your field interests: the authors are grateful to all the clinicians helped. Manic-Depressive Association 2000 survey of individuals with BD in clinical settings unipolar bipolar... And approved the final manuscript symptoms or behaviors related to marked impairment in. Parts were used to refer to any of several depressive disorders clinical challenges Chinese version of patients! 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